மதிப்பிற்குரிய பாய்/ கரையான்/பீர் அவர்களே,
உங்களுக்கு ஒரு குதிரை மருத்துவத்துறை கேள்வி ஒன்று கேட்க விரும்புகிறேன். In my Endocrinology class, one of my students had a question about her horse. I believe it is castrated but it is still extremely aggressive. Supposedly the vet prescribed Depoprogesterone and she was curious how that would help. I am aware that castration alone will not suppress the aggression as adrenals are also a source of testosterone. However I was curious if in your practice as equine vets or vets if you prescribed progesterone for aggressive horses and if so why and does it work?
Thanks - Gujili
Dear Gujili,
பதிலளிநீக்குMake sure whether the gelding was not a cryptorchid. Sometimes under field conditions it is impossible to remove the testicle which is inside the abdomen, only the one outside is removed and the one inside remain. This results in the gelding behaving like a stallion. I have treated some racing fillies which were aggressive or in estrus with Progesterone(Regumate- Altrenogest) but not treated geldings. I read that this administration of depoprogesterone helps, but the aggressive bahaviour returs once the drug is withdrawn. I will write more soon.
karaiyan.
Dear Gujili,
பதிலளிநீக்குAnything about equines,just ask Karayan only.He is the master in that field.
BHAI.
Hello Karayaan,
பதிலளிநீக்குThanks for the information. I will ask the student if it is really completely castrated;
Gujili
Hi Kumuran,
பதிலளிநீக்குFirstly, I would suggest doing a HCG stimulation test to make sure
that the horse has in fact been castrated. As you well know, the most
common cause of aggression in geldings is the presence of a retained
testicle!! If the horse truly no longer has any testicular tissue, the
aggression can potentially be 'controlled' by using drugs, but in my
experience, a much more effective way is behaviour modification using
specific training techniques. If you are going to use drugs, I would
recommend altrenogest (regumate), a short acting oral synthetic
progesterone rather than depoprogesterone. The idea is that it reduces
serum concentrations of testosterone, but there have been no studies
looking at its effect in geldings which have much lower levels of
circulating testosterone than stallions, and I have not had much luck
with it. In other words, the jury is still out.
Regards
Mike
karaiyan.